Lock solutions in intensive care
Ingredients, efficacy, recommendations
Intensive care units operate in the liminal space between life and death. It is where patients are at their most vulnerable state, often depending on central-venous catheters to survive. To protect those catheters against complications and preserve their functionality, we offer a range of different lock solutions. They are based on a combination of active ingredients to fight off multiple threats with just one product.
Effective prevention in ICU
In intensive care, vascular-access devices literally function as lifelines. They enable the delivery of medication, parenteral nutrition, or haemodialysis while monitoring vital parameters around the clock. But without proper caution, the lifeline can quickly turn into a deathtrap. Catheter-related complications are especially dangerous for critically ill patients with severely weakened immune systems. In this context, prevention is more than a protocol – it is a clinical responsibility.
TauroLock™ solutions come into effect well in advance, keeping catheters clean and safe from the moment of insertion.
Source: Dr. Macarena Jordan, Chile.
Source: Dr. Macarena Jordan, Chile.
Source: Dr. Macarena Jordan, Chile.
All ingredients named above have been approved and recommended in current guidelines (Infusion Therapy SoP 2024, KRINKO 2017).
Please note that our products are to be administered by trained staff with medical expertise and experience. On this premise, we advise the following procedure:
1. Before treatment
- Remove TauroLock™/TauroLock™-HEP100/TauroLock™-U25.000/NutriLock™ and residual blood from the VAD.
- Flush all lumens of the access device with 10 ml of saline and a syringe according to the push-pause technique.
- Start treatment.
2. After treatment
- Flush both lumens with 10 ml of saline according to the push-pause technique.
- Gently tap the ampoule’s neck to remove the lock solution.
- Tilt the ampoule so that you can see a white dot on top and quickly break off the neck.
- When using TauroLock™-U25.000:
Reconstitute the urokinase that is delivered in a separate vial with TauroLock™ withdrawn from the ampoule. TauroLock™-U25.000 must be used immediately after reconstitution.
Draw the TauroLock™ solution from the ampoule into a sterile syringe.
3. In-between treatment sessions
- To ensure the solution’s prophylactic efficacy, slowly instil a volume sufficient to fill the entire lumens of the device.
- You can check the proper filling volume of each lumen as indicated on the device or based on the manufacturer’s instructions.